Cervical intraspinal microstimulation evokes robust forelimb movements before and after injury

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Cervical intraspinal microstimulation evokes robust forelimb movements before and after injury.

OBJECTIVE Intraspinal microstimulation (ISMS) is a promising method for reanimating paralyzed limbs following neurological injury. ISMS within the cervical and lumbar spinal cord is capable of evoking a variety of highly-functional movements prior to injury, but the ability of ISMS to evoke forelimb movements after cervical spinal cord injury is unknown. Here we examine the forelimb movements a...

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Therapeutic intraspinal microstimulation improves forelimb function after cervical contusion injury.

OBJECTIVE Intraspinal microstimulation (ISMS) is a promising method for activating the spinal cord distal to an injury. The objectives of this study were to examine the ability of chronically implanted stimulating wires within the cervical spinal cord to (1) directly produce forelimb movements, and (2) assess whether ISMS stimulation could improve subsequent volitional control of paretic extrem...

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Forelimb movements and muscle responses evoked by microstimulation of cervical spinal cord in sedated monkeys.

Documenting the forelimb responses evoked by stimulating sites in primate cervical spinal cord is significant for understanding spinal circuitry and for potential neuroprosthetic applications involving hand and arm. We examined the forelimb movements and electromyographic (EMG) muscle responses evoked by intraspinal microstimulation in three M. nemestrina monkeys sedated with ketamine. Trains o...

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Final Accepted Version Forelimb movements and muscle responses evoked by microstimulation of cervical spinal cord in sedated monkeys

1 Documenting the forelimb responses evoked by stimulating sites in primate cervical 2 spinal cord is significant for understanding spinal circuitry and for potential neuroprosthetic 3 applications involving hand and arm. We examined the forelimb movements and 4 electromyographic (EMG) muscle responses evoked by intraspinal microstimulation in three M. 5 Nemestrina monkeys sedated with ketamine...

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Bimanual reach to grasp movements after cervical spinal cord injury

Injury to the cervical spinal cord results in bilateral deficits in arm/hand function reducing functional independence and quality of life. To date little research has been undertaken to investigate control strategies of arm/hand movements following cervical spinal cord injury (cSCI). This study aimed to investigate unimanual and bimanual coordination in patients with acute cSCI using 3D kinema...

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ژورنال

عنوان ژورنال: Journal of Neural Engineering

سال: 2013

ISSN: 1741-2560,1741-2552

DOI: 10.1088/1741-2560/10/3/036001